Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4784484..4785138 Replicon chromosome
Accession NZ_CP118155
Organism Pseudomonas chlororaphis strain ATCC 17411

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP78_RS21495 Protein ID WP_124324922.1
Coordinates 4784484..4784834 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP78_RS21500 Protein ID WP_124324923.1
Coordinates 4784824..4785138 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP78_RS21485 (PUP78_21485) 4781235..4782767 + 1533 WP_053279911.1 NADH-quinone oxidoreductase subunit M -
PUP78_RS21490 (PUP78_21490) 4782775..4784238 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
PUP78_RS21495 (PUP78_21495) 4784484..4784834 + 351 WP_124324922.1 toxin Toxin
PUP78_RS21500 (PUP78_21500) 4784824..4785138 + 315 WP_124324923.1 transcriptional regulator Antitoxin
PUP78_RS21505 (PUP78_21505) 4785316..4787058 - 1743 WP_025804713.1 ABC transporter substrate-binding protein -
PUP78_RS21510 (PUP78_21510) 4787109..4787381 - 273 WP_025804714.1 DUF2160 domain-containing protein -
PUP78_RS21515 (PUP78_21515) 4787392..4788192 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
PUP78_RS21520 (PUP78_21520) 4788204..4789070 - 867 WP_124324924.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13791.76 Da        Isoelectric Point: 9.4187

>T272902 WP_124324922.1 NZ_CP118155:4784484-4784834 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGVGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTSHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11921.84 Da        Isoelectric Point: 10.7886

>AT272902 WP_124324923.1 NZ_CP118155:4784824-4785138 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDTLAKERQGKLTLRTHKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References