Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4770215..4770869 Replicon chromosome
Accession NZ_CP118150
Organism Pseudomonas chlororaphis strain DSM 21509

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP49_RS21335 Protein ID WP_231998601.1
Coordinates 4770215..4770565 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP49_RS21340 Protein ID WP_053279913.1
Coordinates 4770555..4770869 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP49_RS21325 (PUP49_21325) 4766965..4768497 + 1533 WP_053279911.1 NADH-quinone oxidoreductase subunit M -
PUP49_RS21330 (PUP49_21330) 4768505..4769968 + 1464 WP_007929613.1 NADH-quinone oxidoreductase subunit NuoN -
PUP49_RS21335 (PUP49_21335) 4770215..4770565 + 351 WP_231998601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP49_RS21340 (PUP49_21340) 4770555..4770869 + 315 WP_053279913.1 XRE family transcriptional regulator Antitoxin
PUP49_RS21345 (PUP49_21345) 4771046..4772788 - 1743 WP_053261847.1 ABC transporter substrate-binding protein -
PUP49_RS21350 (PUP49_21350) 4772839..4773111 - 273 WP_053279914.1 DUF2160 domain-containing protein -
PUP49_RS21355 (PUP49_21355) 4773122..4773922 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
PUP49_RS21360 (PUP49_21360) 4773934..4774800 - 867 WP_053279915.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13859.83 Da        Isoelectric Point: 9.3419

>T272873 WP_231998601.1 NZ_CP118150:4770215-4770565 [Pseudomonas chlororaphis]
MDALFIELPPFQRYRQDYLDDELFRSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGSAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11903.87 Da        Isoelectric Point: 10.7886

>AT272873 WP_053279913.1 NZ_CP118150:4770555-4770869 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDALAKERQGKLTLRTHKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATILIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References