272866

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4672341..4672995 Replicon chromosome
Accession NZ_CP118149
Organism Pseudomonas chlororaphis strain NCCB 60037

Toxin (Protein)


Gene name higB Uniprot ID A0A554PC23
Locus tag PUP59_RS21080 Protein ID WP_041986396.1
Coordinates 4672341..4672691 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP59_RS21085 Protein ID WP_016701900.1
Coordinates 4672681..4672995 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP59_RS21070 (PUP59_21070) 4669091..4670623 + 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -
PUP59_RS21075 (PUP59_21075) 4670631..4672094 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
PUP59_RS21080 (PUP59_21080) 4672341..4672691 + 351 WP_041986396.1 toxin Toxin
PUP59_RS21085 (PUP59_21085) 4672681..4672995 + 315 WP_016701900.1 transcriptional regulator Antitoxin
PUP59_RS21090 (PUP59_21090) 4673162..4674904 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
PUP59_RS21095 (PUP59_21095) 4675068..4675340 - 273 WP_009049795.1 DUF2160 domain-containing protein -
PUP59_RS21100 (PUP59_21100) 4675351..4676151 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
PUP59_RS21105 (PUP59_21105) 4676163..4677029 - 867 WP_041986252.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13861.80 Da        Isoelectric Point: 8.5032

>T272866 WP_041986396.1 NZ_CP118149:4672341-4672691 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTDGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11929.90 Da        Isoelectric Point: 10.6052

>AT272866 WP_016701900.1 NZ_CP118149:4672681-4672995 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRINTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554PC23

Antitoxin

Source ID Structure

References