272859

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4633287..4633941 Replicon chromosome
Accession NZ_CP118148
Organism Pseudomonas chlororaphis strain NCCB 880622

Toxin (Protein)


Gene name higB Uniprot ID A0A554PC23
Locus tag PUP58_RS20710 Protein ID WP_041986396.1
Coordinates 4633287..4633637 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP58_RS20715 Protein ID WP_016701900.1
Coordinates 4633627..4633941 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP58_RS20700 (PUP58_20700) 4630037..4631569 + 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -
PUP58_RS20705 (PUP58_20705) 4631577..4633040 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
PUP58_RS20710 (PUP58_20710) 4633287..4633637 + 351 WP_041986396.1 toxin Toxin
PUP58_RS20715 (PUP58_20715) 4633627..4633941 + 315 WP_016701900.1 transcriptional regulator Antitoxin
PUP58_RS20720 (PUP58_20720) 4634108..4635850 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
PUP58_RS20725 (PUP58_20725) 4636014..4636286 - 273 WP_009049795.1 DUF2160 domain-containing protein -
PUP58_RS20730 (PUP58_20730) 4636297..4637097 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
PUP58_RS20735 (PUP58_20735) 4637109..4637975 - 867 WP_274319037.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13861.80 Da        Isoelectric Point: 8.5032

>T272859 WP_041986396.1 NZ_CP118148:4633287-4633637 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTDGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11929.90 Da        Isoelectric Point: 10.6052

>AT272859 WP_016701900.1 NZ_CP118148:4633627-4633941 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRINTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554PC23

Antitoxin

Source ID Structure

References