Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 784147..784841 Replicon chromosome
Accession NZ_CP118146
Organism Pseudomonas chlororaphis strain ATCC 174152

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP66_RS03555 Protein ID WP_097134270.1
Coordinates 784147..784443 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP66_RS03560 Protein ID WP_009041852.1
Coordinates 784440..784841 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP66_RS03520 (PUP66_03520) 779768..780313 - 546 WP_007926837.1 hypothetical protein -
PUP66_RS03525 (PUP66_03525) 780310..780564 - 255 WP_007926835.1 acyl carrier protein -
PUP66_RS03530 (PUP66_03530) 780574..780834 - 261 WP_007926834.1 phosphopantetheine-binding protein -
PUP66_RS03535 (PUP66_03535) 780809..781624 - 816 WP_114760259.1 lysophospholipid acyltransferase family protein -
PUP66_RS03540 (PUP66_03540) 781600..782331 - 732 WP_037004440.1 beta-ketoacyl synthase chain length factor -
PUP66_RS03545 (PUP66_03545) 782666..783436 + 771 WP_009041850.1 ParA family protein -
PUP66_RS03550 (PUP66_03550) 783475..783909 - 435 WP_062823885.1 thioredoxin TrxC -
PUP66_RS03555 (PUP66_03555) 784147..784443 + 297 WP_097134270.1 type II toxin-antitoxin system HigB family toxin Toxin
PUP66_RS03560 (PUP66_03560) 784440..784841 + 402 WP_009041852.1 transcriptional regulator Antitoxin
PUP66_RS03565 (PUP66_03565) 784845..786308 - 1464 WP_097134272.1 YdiU family protein -
PUP66_RS03570 (PUP66_03570) 786357..789707 - 3351 WP_114760260.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Antitoxin HigA

(15-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11560.36 Da        Isoelectric Point: 10.6515

>T272843 WP_097134270.1 NZ_CP118146:784147-784443 [Pseudomonas chlororaphis]
MHIITAKRIWEAKSRWPQSANALETWYRKAKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14854.92 Da        Isoelectric Point: 4.5430

>AT272843 WP_009041852.1 NZ_CP118146:784440-784841 [Pseudomonas chlororaphis]
MNVLVKQAADHWHFVAPVLRKPKTEADYDALVAALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References