Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 770965..771659 Replicon chromosome
Accession NZ_CP118145
Organism Pseudomonas chlororaphis strain ATCC 17417

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP75_RS03505 Protein ID WP_097134270.1
Coordinates 770965..771261 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP75_RS03510 Protein ID WP_009041852.1
Coordinates 771258..771659 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP75_RS03470 (PUP75_03470) 766586..767131 - 546 WP_007926837.1 hypothetical protein -
PUP75_RS03475 (PUP75_03475) 767128..767382 - 255 WP_007926835.1 acyl carrier protein -
PUP75_RS03480 (PUP75_03480) 767392..767652 - 261 WP_007926834.1 phosphopantetheine-binding protein -
PUP75_RS03485 (PUP75_03485) 767627..768442 - 816 WP_009041848.1 lysophospholipid acyltransferase family protein -
PUP75_RS03490 (PUP75_03490) 768418..769149 - 732 WP_253362396.1 beta-ketoacyl synthase chain length factor -
PUP75_RS03495 (PUP75_03495) 769484..770254 + 771 WP_009041850.1 ParA family protein -
PUP75_RS03500 (PUP75_03500) 770293..770727 - 435 WP_274335676.1 thioredoxin TrxC -
PUP75_RS03505 (PUP75_03505) 770965..771261 + 297 WP_097134270.1 type II toxin-antitoxin system HigB family toxin Toxin
PUP75_RS03510 (PUP75_03510) 771258..771659 + 402 WP_009041852.1 transcriptional regulator Antitoxin
PUP75_RS03515 (PUP75_03515) 771663..773126 - 1464 WP_062823882.1 YdiU family protein -
PUP75_RS03520 (PUP75_03520) 773175..776525 - 3351 WP_085533569.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Antitoxin HigA

(15-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11560.36 Da        Isoelectric Point: 10.6515

>T272835 WP_097134270.1 NZ_CP118145:770965-771261 [Pseudomonas chlororaphis]
MHIITAKRIWEAKSRWPQSANALETWYRKAKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14854.92 Da        Isoelectric Point: 4.5430

>AT272835 WP_009041852.1 NZ_CP118145:771258-771659 [Pseudomonas chlororaphis]
MNVLVKQAADHWHFVAPVLRKPKTEADYDALVAALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References