272816

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6799649..6800343 Replicon chromosome
Accession NZ_CP118142
Organism Pseudomonas chlororaphis strain ATCC 17809

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP81_RS30825 Protein ID WP_053268076.1
Coordinates 6800047..6800343 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP81_RS30820 Protein ID WP_124323351.1
Coordinates 6799649..6800050 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP81_RS30810 (PUP81_30810) 6794785..6798132 + 3348 WP_124323353.1 mechanosensitive channel MscK -
PUP81_RS30815 (PUP81_30815) 6798181..6799644 + 1464 WP_124323352.1 YdiU family protein -
PUP81_RS30820 (PUP81_30820) 6799649..6800050 - 402 WP_124323351.1 transcriptional regulator Antitoxin
PUP81_RS30825 (PUP81_30825) 6800047..6800343 - 297 WP_053268076.1 type II toxin-antitoxin system HigB family toxin Toxin
PUP81_RS30830 (PUP81_30830) 6800581..6801015 + 435 WP_124323350.1 thioredoxin TrxC -
PUP81_RS30835 (PUP81_30835) 6801141..6801911 - 771 WP_097305890.1 ParA family protein -
PUP81_RS30840 (PUP81_30840) 6802243..6802974 + 732 WP_036998144.1 beta-ketoacyl synthase chain length factor -
PUP81_RS30845 (PUP81_30845) 6802950..6803765 + 816 WP_124323349.1 lysophospholipid acyltransferase family protein -
PUP81_RS30850 (PUP81_30850) 6803740..6804000 + 261 WP_025808152.1 phosphopantetheine-binding protein -
PUP81_RS30855 (PUP81_30855) 6804010..6804264 + 255 WP_007926835.1 acyl carrier protein -
PUP81_RS30860 (PUP81_30860) 6804261..6804806 + 546 WP_025808153.1 membrane protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11588.41 Da        Isoelectric Point: 10.6515

>T272816 WP_053268076.1 NZ_CP118142:c6800343-6800047 [Pseudomonas chlororaphis]
MHIITAKRIWEAKSRWPQSANALETWYRKVKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR

Download         Length: 297 bp


Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14925.01 Da        Isoelectric Point: 4.5517

>AT272816 WP_124323351.1 NZ_CP118142:c6800050-6799649 [Pseudomonas chlororaphis]
MNVLVRQAAEHWHFVAPVLRKPKTEADYDALVVALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI

Download         Length: 402 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References