Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 6799649..6800343 | Replicon | chromosome |
Accession | NZ_CP118142 | ||
Organism | Pseudomonas chlororaphis strain ATCC 17809 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | PUP81_RS30825 | Protein ID | WP_053268076.1 |
Coordinates | 6800047..6800343 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | PUP81_RS30820 | Protein ID | WP_124323351.1 |
Coordinates | 6799649..6800050 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PUP81_RS30810 (PUP81_30810) | 6794785..6798132 | + | 3348 | WP_124323353.1 | mechanosensitive channel MscK | - |
PUP81_RS30815 (PUP81_30815) | 6798181..6799644 | + | 1464 | WP_124323352.1 | YdiU family protein | - |
PUP81_RS30820 (PUP81_30820) | 6799649..6800050 | - | 402 | WP_124323351.1 | transcriptional regulator | Antitoxin |
PUP81_RS30825 (PUP81_30825) | 6800047..6800343 | - | 297 | WP_053268076.1 | type II toxin-antitoxin system HigB family toxin | Toxin |
PUP81_RS30830 (PUP81_30830) | 6800581..6801015 | + | 435 | WP_124323350.1 | thioredoxin TrxC | - |
PUP81_RS30835 (PUP81_30835) | 6801141..6801911 | - | 771 | WP_097305890.1 | ParA family protein | - |
PUP81_RS30840 (PUP81_30840) | 6802243..6802974 | + | 732 | WP_036998144.1 | beta-ketoacyl synthase chain length factor | - |
PUP81_RS30845 (PUP81_30845) | 6802950..6803765 | + | 816 | WP_124323349.1 | lysophospholipid acyltransferase family protein | - |
PUP81_RS30850 (PUP81_30850) | 6803740..6804000 | + | 261 | WP_025808152.1 | phosphopantetheine-binding protein | - |
PUP81_RS30855 (PUP81_30855) | 6804010..6804264 | + | 255 | WP_007926835.1 | acyl carrier protein | - |
PUP81_RS30860 (PUP81_30860) | 6804261..6804806 | + | 546 | WP_025808153.1 | membrane protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11588.41 Da Isoelectric Point: 10.6515
>T272816 WP_053268076.1 NZ_CP118142:c6800343-6800047 [Pseudomonas chlororaphis]
MHIITAKRIWEAKSRWPQSANALETWYRKVKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR
MHIITAKRIWEAKSRWPQSANALETWYRKVKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR
Download Length: 297 bp
Antitoxin
Download Length: 134 a.a. Molecular weight: 14925.01 Da Isoelectric Point: 4.5517
>AT272816 WP_124323351.1 NZ_CP118142:c6800050-6799649 [Pseudomonas chlororaphis]
MNVLVRQAAEHWHFVAPVLRKPKTEADYDALVVALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI
MNVLVRQAAEHWHFVAPVLRKPKTEADYDALVVALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI
Download Length: 402 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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