272778

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4672366..4673020 Replicon chromosome
Accession NZ_CP118136
Organism Pseudomonas chlororaphis strain NCCB 60038

Toxin (Protein)


Gene name higB Uniprot ID A0A554PC23
Locus tag PUP52_RS21080 Protein ID WP_041986396.1
Coordinates 4672366..4672716 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP52_RS21085 Protein ID WP_016701900.1
Coordinates 4672706..4673020 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP52_RS21070 (PUP52_21070) 4669116..4670648 + 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -
PUP52_RS21075 (PUP52_21075) 4670656..4672119 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
PUP52_RS21080 (PUP52_21080) 4672366..4672716 + 351 WP_041986396.1 toxin Toxin
PUP52_RS21085 (PUP52_21085) 4672706..4673020 + 315 WP_016701900.1 transcriptional regulator Antitoxin
PUP52_RS21090 (PUP52_21090) 4673187..4674929 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
PUP52_RS21095 (PUP52_21095) 4675093..4675365 - 273 WP_009049795.1 DUF2160 domain-containing protein -
PUP52_RS21100 (PUP52_21100) 4675376..4676176 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
PUP52_RS21105 (PUP52_21105) 4676188..4677054 - 867 WP_041986252.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13861.80 Da        Isoelectric Point: 8.5032

>T272778 WP_041986396.1 NZ_CP118136:4672366-4672716 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTDGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11929.90 Da        Isoelectric Point: 10.6052

>AT272778 WP_016701900.1 NZ_CP118136:4672706-4673020 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRINTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554PC23

Antitoxin

Source ID Structure

References