Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3898328..3898982 Replicon chromosome
Accession NZ_CP118134
Organism Pseudomonas synxantha strain ATCC 17413

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP72_RS17480 Protein ID WP_046068644.1
Coordinates 3898328..3898678 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0W0N117
Locus tag PUP72_RS17485 Protein ID WP_014718915.1
Coordinates 3898668..3898982 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP72_RS17470 (PUP72_17470) 3895087..3896619 + 1533 WP_034120261.1 NADH-quinone oxidoreductase subunit M -
PUP72_RS17475 (PUP72_17475) 3896627..3898090 + 1464 WP_043046579.1 NADH-quinone oxidoreductase subunit NuoN -
PUP72_RS17480 (PUP72_17480) 3898328..3898678 + 351 WP_046068644.1 toxin Toxin
PUP72_RS17485 (PUP72_17485) 3898668..3898982 + 315 WP_014718915.1 XRE family transcriptional regulator Antitoxin
PUP72_RS17490 (PUP72_17490) 3899042..3899794 - 753 WP_274354886.1 outer membrane beta-barrel protein -
PUP72_RS17495 (PUP72_17495) 3899920..3900753 - 834 WP_274354887.1 arylamine N-acetyltransferase -
PUP72_RS17500 (PUP72_17500) 3900872..3901108 + 237 WP_005789137.1 hypothetical protein -
PUP72_RS17505 (PUP72_17505) 3901139..3901345 - 207 WP_046068647.1 DUF6021 family protein -
PUP72_RS17510 (PUP72_17510) 3901358..3901537 - 180 WP_046068648.1 hypothetical protein -
PUP72_RS17515 (PUP72_17515) 3901652..3902173 + 522 WP_046068649.1 DUF3087 family protein -
PUP72_RS17520 (PUP72_17520) 3902181..3903311 - 1131 WP_046068650.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13794.71 Da        Isoelectric Point: 9.7336

>T272762 WP_046068644.1 NZ_CP118134:3898328-3898678 [Pseudomonas synxantha]
MDALFIELPAFERHRKDYLSEELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEHSDLTPHHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11755.58 Da        Isoelectric Point: 10.6525

>AT272762 WP_014718915.1 NZ_CP118134:3898668-3898982 [Pseudomonas synxantha]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0N117

References