Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 294627..295140 Replicon chromosome
Accession NZ_CP118097
Organism Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MGCS35922_RS01630 Protein ID WP_084916229.1
Coordinates 294627..294881 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MGCS35922_RS01635 Protein ID WP_003053797.1
Coordinates 294874..295140 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MGCS35922_RS01600 (MGCS35922_00650) 290869..291279 - 411 WP_003053802.1 conjugal transfer protein -
MGCS35922_RS01605 (MGCS35922_00652) 291282..291506 - 225 WP_003053785.1 hypothetical protein -
MGCS35922_RS01610 (MGCS35922_00654) 291510..292520 - 1011 WP_022554213.1 conjugal transfer protein -
MGCS35922_RS01615 (MGCS35922_00656) 292532..293068 - 537 WP_003053800.1 hypothetical protein -
MGCS35922_RS01620 (MGCS35922_00658) 293095..293325 - 231 WP_003053793.1 hypothetical protein -
MGCS35922_RS01625 (MGCS35922_00660) 293345..294571 - 1227 WP_084916231.1 replication initiation factor domain-containing protein -
MGCS35922_RS01630 (MGCS35922_00662) 294627..294881 - 255 WP_084916229.1 Txe/YoeB family addiction module toxin Toxin
MGCS35922_RS01635 (MGCS35922_00664) 294874..295140 - 267 WP_003053797.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MGCS35922_RS01640 (MGCS35922_00666) 295405..297090 - 1686 WP_084916228.1 FtsK/SpoIIIE domain-containing protein -
MGCS35922_RS01645 (MGCS35922_00668) 297107..297568 - 462 WP_003056467.1 hypothetical protein -
MGCS35922_RS01650 (MGCS35922_00670) 297587..297883 - 297 WP_003056470.1 hypothetical protein -
MGCS35922_RS01655 (MGCS35922_00672) 297923..298168 - 246 WP_003056472.1 hypothetical protein -
MGCS35922_RS01660 (MGCS35922_00674) 298741..299082 + 342 WP_110408064.1 helix-turn-helix transcriptional regulator -
MGCS35922_RS01665 (MGCS35922_00676) 299286..299591 + 306 WP_014612001.1 hypothetical protein -
MGCS35922_RS01670 (MGCS35922_00678) 299626..299985 - 360 WP_003053656.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 269102..310864 41762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10502.78 Da        Isoelectric Point: 8.4060

>T272754 WP_084916229.1 NZ_CP118097:c294881-294627 [Streptococcus dysgalactiae subsp. equisimilis]
MFNFTEEAWEDYTSWQREDKKNLKRINRLIEDIKRHPFEGIGKPEPLKYRYSGAWSRRITDEHRLVYTVEQNDIYFLSFR
DHYK

Download         Length: 255 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10402.81 Da        Isoelectric Point: 4.5216

>AT272754 WP_003053797.1 NZ_CP118097:c295140-294874 [Streptococcus dysgalactiae subsp. equisimilis]
MEAVVYSNFRNNLKDYMKKVNDEYEPLMVVNKNPEENIVVLSKDNWDSIQETIRIMNNEYLSDKVLSGLEQVKQKKVTQH
QLLEVEDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References