Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 692728..693242 Replicon chromosome
Accession NZ_CP118092
Organism Limosilactobacillus fermentum strain VSI05

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PUW73_RS03360 Protein ID WP_046949245.1
Coordinates 692979..693242 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID C0WV67
Locus tag PUW73_RS03355 Protein ID WP_003684069.1
Coordinates 692728..692982 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW73_RS03340 (PUW73_03340) 688363..689502 + 1140 WP_178958848.1 IS30 family transposase -
PUW73_RS03345 (PUW73_03345) 689806..691158 + 1353 WP_274983054.1 transposase -
PUW73_RS03350 (PUW73_03350) 691273..692493 + 1221 WP_274982864.1 IS256 family transposase -
PUW73_RS03355 (PUW73_03355) 692728..692982 + 255 WP_003684069.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUW73_RS03360 (PUW73_03360) 692979..693242 + 264 WP_046949245.1 Txe/YoeB family addiction module toxin Toxin
PUW73_RS03365 (PUW73_03365) 693652..694773 - 1122 WP_274983055.1 PTS sugar transporter subunit IIC -
PUW73_RS03370 (PUW73_03370) 694937..696391 - 1455 WP_274982839.1 transposase -
PUW73_RS03375 (PUW73_03375) 696768..698165 - 1398 WP_024271998.1 Na+/H+ antiporter NhaC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(25-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-55)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10284.99 Da        Isoelectric Point: 10.3799

>T272751 WP_046949245.1 NZ_CP118092:692979-693242 [Limosilactobacillus fermentum]
MSYAIKLKRSANKDLKKIKGSYLEKSFLQIIEQLRKDPLAPNQGFEKLVPPIKGFYSRRINIQHRLVYKVDQDTQTVIIY
SAWSHYE

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9745.04 Da        Isoelectric Point: 4.4237

>AT272751 WP_003684069.1 NZ_CP118092:692728-692982 [Limosilactobacillus fermentum]
MDQIVTPTQARKDLFKIIKRINENNEPVVIKPTKADEKSVVVIGEDDWKAIQETLFLVNHGVDKQIKERENEPLDDFDDV
WGQL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A806T868

References