Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2509518..2509715 Replicon chromosome
Accession NZ_CP117979
Organism Staphylococcus aureus strain B-41012

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PT798_RS12250 Protein ID WP_001802298.1
Coordinates 2509611..2509715 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2509518..2509556 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT798_RS12225 2505693..2506358 - 666 WP_001024095.1 SDR family oxidoreductase -
PT798_RS12230 2506510..2506830 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PT798_RS12235 2506832..2507812 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
PT798_RS12240 2508078..2509169 + 1092 WP_000495681.1 hypothetical protein -
PT798_RS12245 2509498..2509572 + 75 Protein_2376 hypothetical protein -
- 2509518..2509556 + 39 - - Antitoxin
PT798_RS12250 2509611..2509715 - 105 WP_001802298.1 hypothetical protein Toxin
PT798_RS12255 2510395..2510553 + 159 WP_001792784.1 hypothetical protein -
PT798_RS12260 2511211..2512068 - 858 WP_000370930.1 HAD family hydrolase -
PT798_RS12265 2512136..2512918 - 783 WP_000908180.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T272643 WP_001802298.1 NZ_CP117979:c2509715-2509611 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT272643 NZ_CP117979:2509518-2509556 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References