Detailed information of TA system TA272639

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2229299..2229479
• Replicon: chromosome
• Accession: NZ_CP117979
• Organism: Staphylococcus aureus strain B-41012

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: PT798_RS10665
• Protein ID: WP_001801861.1
• Coordinates: 2229299..2229394 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2229422..2229479 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PT798_RS10635	2225354..2225980	+	627	WP_000669028.1	hypothetical protein	-
PT798_RS10640	2226067..2226750	+	684	WP_000957233.1	exotoxin beta-grasp domain-containing protein	-
PT798_RS10645	2226777..2227529	+	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
PT798_RS10650	2227661..2228287	-	627	Protein_2100	ImmA/IrrE family metallo-endopeptidase	-
PT798_RS10655	2228401..2228847	-	447	WP_000747805.1	DUF1433 domain-containing protein	-
PT798_RS10660	2229023..2229154	-	132	WP_001808010.1	hypothetical protein	-
PT798_RS10665	2229299..2229394	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2229422..2229479	-	58	-	-	Antitoxin
PT798_RS10670	2229517..2229615	+	99	Protein_2104	hypothetical protein	-
PT798_RS10675	2230045..2231169	-	1125	WP_223876714.1	hypothetical protein	-
PT798_RS10680	2231231..2231740	-	510	WP_223289274.1	hypothetical protein	-
PT798_RS10685	2231718..2232571	-	854	Protein_2107	DNA adenine methylase	-
PT798_RS10690	2232610..2233875	-	1266	WP_000072555.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	2222796..2250762	27966

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T272639 WP_001801861.1 NZ_CP117979:2229299-2229394 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT272639 NZ_CP117979:c2229479-2229422 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin