Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2229299..2229479 Replicon chromosome
Accession NZ_CP117979
Organism Staphylococcus aureus strain B-41012

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag PT798_RS10665 Protein ID WP_001801861.1
Coordinates 2229299..2229394 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2229422..2229479 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT798_RS10635 2225354..2225980 + 627 WP_000669028.1 hypothetical protein -
PT798_RS10640 2226067..2226750 + 684 WP_000957233.1 exotoxin beta-grasp domain-containing protein -
PT798_RS10645 2226777..2227529 + 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
PT798_RS10650 2227661..2228287 - 627 Protein_2100 ImmA/IrrE family metallo-endopeptidase -
PT798_RS10655 2228401..2228847 - 447 WP_000747805.1 DUF1433 domain-containing protein -
PT798_RS10660 2229023..2229154 - 132 WP_001808010.1 hypothetical protein -
PT798_RS10665 2229299..2229394 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2229422..2229479 - 58 - - Antitoxin
PT798_RS10670 2229517..2229615 + 99 Protein_2104 hypothetical protein -
PT798_RS10675 2230045..2231169 - 1125 WP_223876714.1 hypothetical protein -
PT798_RS10680 2231231..2231740 - 510 WP_223289274.1 hypothetical protein -
PT798_RS10685 2231718..2232571 - 854 Protein_2107 DNA adenine methylase -
PT798_RS10690 2232610..2233875 - 1266 WP_000072555.1 restriction endonuclease subunit S -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 2222796..2250762 27966


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T272639 WP_001801861.1 NZ_CP117979:2229299-2229394 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp


Antitoxin


Download         Length: 58 bp

>AT272639 NZ_CP117979:c2229479-2229422 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References