Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2644170..2644364 Replicon chromosome
Accession NZ_CP117970
Organism Enterococcus faecalis strain B-537

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag PT722_RS12730 Protein ID WP_015543884.1
Coordinates 2644170..2644265 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2644300..2644364 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT722_RS12710 (2639347) 2639347..2640462 + 1116 WP_002364956.1 FAD-dependent oxidoreductase -
PT722_RS12715 (2640531) 2640531..2641685 - 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
PT722_RS12720 (2641700) 2641700..2642137 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
PT722_RS12725 (2642152) 2642152..2643924 - 1773 WP_002391520.1 PTS mannitol-specific transporter subunit IIBC -
PT722_RS12730 (2644170) 2644170..2644265 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- (2644300) 2644300..2644364 - 65 NuclAT_8 - Antitoxin
PT722_RS12735 (2644535) 2644535..2644969 - 435 WP_002358391.1 PTS sugar transporter subunit IIA -
PT722_RS12740 (2644980) 2644980..2647013 - 2034 WP_002355275.1 BglG family transcription antiterminator -
PT722_RS12745 (2647004) 2647004..2648746 - 1743 WP_002391519.1 PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T272587 WP_015543884.1 NZ_CP117970:2644170-2644265 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

Antitoxin


Download         Length: 65 bp

>AT272587 NZ_CP117970:c2644364-2644300 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References