272566

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1853965..1854482 Replicon chromosome
Accession NZ_CP117964
Organism Fusobacterium nucleatum strain 2/1/50A

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2B7YTI4
Locus tag PT307_RS08955 Protein ID WP_008795001.1
Coordinates 1854225..1854482 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2B7YT06
Locus tag PT307_RS08950 Protein ID WP_008795000.1
Coordinates 1853965..1854222 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT307_RS08930 1849097..1851190 + 2094 WP_009007598.1 outer membrane protein assembly factor -
PT307_RS08935 1851231..1851704 + 474 WP_008701805.1 OmpH family outer membrane protein -
PT307_RS08940 1851732..1852730 + 999 WP_009007597.1 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase -
PT307_RS08945 1852769..1853845 + 1077 WP_009007596.1 glycerophosphodiester phosphodiesterase -
PT307_RS08950 1853965..1854222 + 258 WP_008795000.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PT307_RS08955 1854225..1854482 + 258 WP_008795001.1 Txe/YoeB family addiction module toxin Toxin
PT307_RS08960 1854598..1855674 + 1077 WP_009007595.1 DHH family phosphoesterase -
PT307_RS08965 1855906..1856643 + 738 WP_009007594.1 tRNA pseudouridine(38-40) synthase TruA -
PT307_RS08970 1856792..1857289 + 498 WP_009007593.1 POTRA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10240.78 Da        Isoelectric Point: 8.0412

>T272566 WP_008795001.1 NZ_CP117964:1854225-1854482 [Fusobacterium nucleatum]
MKIIWDDEAWKEYVEWQTIDRKIVKKINELIKDIQRNGNEGIGKPEPLQHELSGYWSRRITEKHRLIYFITENQLVIIGC
SGHYK

Download         Length: 258 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10266.50 Da        Isoelectric Point: 4.5702

>AT272566 WP_008795000.1 NZ_CP117964:1853965-1854222 [Fusobacterium nucleatum]
MIATNYSEVRNNLKTYCDKATKDYETIIITRKNNENVVLMSEEEYNNLMENLYIMSNKDYYNELVRRKKEIEKGNYTEHD
LIEVD

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2B7YTI4

Antitoxin

Source ID Structure
AlphaFold DB A0A2B7YT06

References