Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1307558..1308072 Replicon chromosome
Accession NZ_CP117933
Organism Limosilactobacillus fermentum strain B-1840

Toxin (Protein)


Gene name yoeB Uniprot ID C0WV68
Locus tag PTQ87_RS06725 Protein ID WP_003684072.1
Coordinates 1307558..1307821 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID C0WV67
Locus tag PTQ87_RS06730 Protein ID WP_003684069.1
Coordinates 1307818..1308072 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTQ87_RS06710 1303034..1303816 + 783 WP_035431216.1 arginine deiminase-related protein -
PTQ87_RS06715 1304204..1305601 + 1398 WP_003684076.1 Na+/H+ antiporter NhaC family protein -
PTQ87_RS06720 1306027..1307148 + 1122 WP_080543055.1 PTS sugar transporter subunit IIC -
PTQ87_RS06725 1307558..1307821 - 264 WP_003684072.1 Txe/YoeB family addiction module toxin Toxin
PTQ87_RS06730 1307818..1308072 - 255 WP_003684069.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PTQ87_RS06735 1308242..1308940 + 699 WP_015639439.1 helix-turn-helix domain-containing protein -
PTQ87_RS06740 1308877..1309779 + 903 WP_274235353.1 IS3 family transposase -
PTQ87_RS06745 1310342..1311694 - 1353 WP_003684067.1 IS4 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(25-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-55)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10301.03 Da        Isoelectric Point: 10.3799

>T272472 WP_003684072.1 NZ_CP117933:c1307821-1307558 [Limosilactobacillus fermentum]
MSYAIKLKRSANKDLKKIKGSYLEKSFLQIIEQLRKDPLAPNQGFEKLVLPIKGFYSRRINIQHRLVYKVDQDTQTVIIY
SAWSHYE

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9745.04 Da        Isoelectric Point: 4.4237

>AT272472 WP_003684069.1 NZ_CP117933:c1308072-1307818 [Limosilactobacillus fermentum]
MDQIVTPTQARKDLFKIIKRINENNEPVVIKPTKADEKSVVVIGEDDWKAIQETLFLVNHGVDKQIKERENEPLDDFDDV
WGQL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0WV68

Antitoxin

Source ID Structure
AlphaFold DB A0A806T868

References