Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1708759..1709419 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PSR30_RS07555 Protein ID WP_274215162.1
Coordinates 1708759..1709112 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PSR30_RS07560 Protein ID WP_274215163.1
Coordinates 1709117..1709419 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS07535 (PSR30_07535) 1705072..1706328 + 1257 WP_274215161.1 multidrug effflux MFS transporter -
PSR30_RS07540 (PSR30_07540) 1706374..1707213 - 840 WP_044203470.1 glutathione-dependent disulfide-bond oxidoreductase -
PSR30_RS07545 (PSR30_07545) 1707378..1707989 - 612 WP_180781488.1 NAD(P)-dependent oxidoreductase -
PSR30_RS07550 (PSR30_07550) 1708092..1708532 + 441 WP_180781487.1 helix-turn-helix domain-containing protein -
PSR30_RS07555 (PSR30_07555) 1708759..1709112 + 354 WP_274215162.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSR30_RS07560 (PSR30_07560) 1709117..1709419 + 303 WP_274215163.1 XRE family transcriptional regulator Antitoxin
PSR30_RS07565 (PSR30_07565) 1709456..1710460 - 1005 WP_274215164.1 threonine/serine dehydratase -
PSR30_RS07570 (PSR30_07570) 1710513..1710863 + 351 WP_274215165.1 metalloregulator ArsR/SmtB family transcription factor -
PSR30_RS07575 (PSR30_07575) 1711120..1711953 + 834 WP_274215166.1 SDR family oxidoreductase -
PSR30_RS07580 (PSR30_07580) 1712053..1712925 + 873 WP_274215431.1 formylglycine-generating enzyme family protein -
PSR30_RS07585 (PSR30_07585) 1713087..1714076 + 990 WP_274215167.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-81)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13718.76 Da        Isoelectric Point: 9.9440

>T272445 WP_274215162.1 NZ_CP117874:1708759-1709112 [Pectobacterium carotovorum subsp. carotovorum]
VWRIETTDVFDRWFSALNDRERACVLAALIVLREKGPMLSRPYADTVKGSRYSNMKELRIQSRGTPIRAFFAFDPYRTGI
LLCAGNKSGNEKRFYDEMLPFAERELTNYLKKSEKRE

Download         Length: 354 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11314.22 Da        Isoelectric Point: 5.6573

>AT272445 WP_274215163.1 NZ_CP117874:1709117-1709419 [Pectobacterium carotovorum subsp. carotovorum]
MGRTLEQLLADEKPEVVVDAHAIATEMLLNIHLAELRERVQKTQVEMAQMLGLKQPTVAVMEKPGRDLKLSTLKRYVEAT
GSKLRLDVELPDGSHYEFML

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References