Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 25602..26259 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PSR30_RS00115 Protein ID WP_182813787.1
Coordinates 25888..26259 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PSR30_RS00110 Protein ID WP_103862387.1
Coordinates 25602..25901 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS00090 (PSR30_00090) 20837..21844 + 1008 WP_274214619.1 nucleoside hydrolase -
PSR30_RS00095 (PSR30_00095) 21844..22821 + 978 WP_010296900.1 ABC transporter permease -
PSR30_RS00100 (PSR30_00100) 22818..23726 + 909 WP_274214620.1 ABC transporter permease -
PSR30_RS00105 (PSR30_00105) 23766..25565 + 1800 WP_274214621.1 ABC transporter ATP-binding protein -
PSR30_RS00110 (PSR30_00110) 25602..25901 - 300 WP_103862387.1 XRE family transcriptional regulator Antitoxin
PSR30_RS00115 (PSR30_00115) 25888..26259 - 372 WP_182813787.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSR30_RS00120 (PSR30_00120) 26597..27295 + 699 WP_274215488.1 D-galactonate utilization transcriptional regulator DgoR -
PSR30_RS00125 (PSR30_00125) 27292..28188 + 897 WP_226509703.1 2-dehydro-3-deoxygalactonokinase -
PSR30_RS00130 (PSR30_00130) 28172..28789 + 618 WP_039508229.1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase -
PSR30_RS00135 (PSR30_00135) 28786..29934 + 1149 WP_039508227.1 galactonate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-108)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 14164.08 Da        Isoelectric Point: 4.8510

>T272435 WP_182813787.1 NZ_CP117874:c26259-25888 [Pectobacterium carotovorum subsp. carotovorum]
MAWEIVTRALFDTWFYEQNEAVQEEVLAHLAILEEDGPQLGRPQVDQIKGSKYKNMKELRVQVGGHPFRTFFAFDRTRKA
IILCAGDKKGEDEKLFYERMIKIADAEFTSHLISPEAKEDGDA

Download         Length: 372 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11034.05 Da        Isoelectric Point: 10.6442

>AT272435 WP_103862387.1 NZ_CP117874:c25901-25602 [Pectobacterium carotovorum subsp. carotovorum]
MATLKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVDNDPKLSTLKRYVTALG
GKLTLDVTLPDGKRIALTL

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References