Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 31134..31650 Replicon chromosome
Accession NZ_CP117811
Organism Lentisphaera profundi strain SAORIC-696

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PQO03_RS00135 Protein ID WP_274150442.1
Coordinates 31384..31650 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PQO03_RS00130 Protein ID WP_274150441.1
Coordinates 31134..31391 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQO03_RS00110 (PQO03_00110) 26340..27230 + 891 WP_274150437.1 class I SAM-dependent methyltransferase -
PQO03_RS00115 (PQO03_00115) 27217..27822 + 606 WP_274150438.1 hypothetical protein -
PQO03_RS00120 (PQO03_00120) 27929..28852 + 924 WP_274150439.1 TIGR01777 family oxidoreductase -
PQO03_RS00125 (PQO03_00125) 28975..30072 + 1098 WP_274150440.1 transposase -
PQO03_RS00130 (PQO03_00130) 31134..31391 + 258 WP_274150441.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PQO03_RS00135 (PQO03_00135) 31384..31650 + 267 WP_274150442.1 Txe/YoeB family addiction module toxin Toxin
PQO03_RS00140 (PQO03_00140) 32468..33847 + 1380 WP_274150443.1 hypothetical protein -
PQO03_RS00145 (PQO03_00145) 33844..34857 + 1014 WP_274150444.1 AAA family ATPase -
PQO03_RS00150 (PQO03_00150) 35046..36539 + 1494 WP_274150445.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - fcl 227..2808340 2808113


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10631.13 Da        Isoelectric Point: 9.6400

>T272278 WP_274150442.1 NZ_CP117811:31384-31650 [Lentisphaera profundi]
MIKKFSDDAWDDYVYWQTQDKKTLKRINLLIKDTERDPFSGIGKPEPLKHNLSGSWSRRIDEKNRMVYRIKKEGDQEILE
IAALRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9658.70 Da        Isoelectric Point: 4.4354

>AT272278 WP_274150441.1 NZ_CP117811:31134-31391 [Lentisphaera profundi]
MQTITYTKARNNLAKEMERVSSDHDYTVITRANQESAVLMSLEDFSSWQETAYLLSSPSNAKRLMRSLEQLDSGGGQVRE
LIEDD

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References