Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3447444..3448259 Replicon chromosome
Accession NZ_CP117798
Organism Proteus mirabilis strain IVRI/FBI/326

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag PT008_RS16460 Protein ID WP_075673429.1
Coordinates 3447786..3448259 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag PT008_RS16455 Protein ID WP_075673430.1
Coordinates 3447444..3447779 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT008_RS16435 (PT008_16435) 3443133..3444557 + 1425 WP_072069056.1 aspartate ammonia-lyase -
PT008_RS16440 (PT008_16440) 3444716..3446041 + 1326 WP_109394971.1 anaerobic C4-dicarboxylate transporter -
PT008_RS16445 (PT008_16445) 3446225..3446797 + 573 WP_098941859.1 transcriptional regulator -
PT008_RS16455 (PT008_16455) 3447444..3447779 + 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
PT008_RS16460 (PT008_16460) 3447786..3448259 + 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
PT008_RS16465 (PT008_16465) 3448570..3449217 + 648 WP_109850424.1 type II CAAX endopeptidase family protein -
PT008_RS16470 (PT008_16470) 3449520..3450155 + 636 WP_109850423.1 DUF1449 family protein -
PT008_RS16475 (PT008_16475) 3450241..3452436 + 2196 WP_109850422.1 flotillin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T272276 WP_075673429.1 NZ_CP117798:3447786-3448259 [Proteus mirabilis]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT272276 WP_075673430.1 NZ_CP117798:3447444-3447779 [Proteus mirabilis]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References