Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4169563..4170065 Replicon chromosome
Accession NZ_CP117750
Organism Enterobacter hormaechei strain 2022CK-00700

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PTC84_RS20180 Protein ID WP_032103793.1
Coordinates 4169811..4170065 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PTC84_RS20175 Protein ID WP_032103791.1
Coordinates 4169563..4169814 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC84_RS20155 (PTC84_20155) 4164659..4164844 + 186 WP_001196016.1 hypothetical protein -
PTC84_RS20160 (PTC84_20160) 4164912..4167008 + 2097 WP_017383654.1 peptidase domain-containing ABC transporter -
PTC84_RS20165 (PTC84_20165) 4167005..4167754 + 750 WP_033487009.1 hypothetical protein -
PTC84_RS20170 (PTC84_20170) 4167761..4169011 + 1251 WP_017693988.1 HlyD family efflux transporter periplasmic adaptor subunit -
PTC84_RS20175 (PTC84_20175) 4169563..4169814 + 252 WP_032103791.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
PTC84_RS20180 (PTC84_20180) 4169811..4170065 + 255 WP_032103793.1 Txe/YoeB family addiction module toxin Toxin
PTC84_RS20185 (PTC84_20185) 4170141..4170458 + 318 WP_032103795.1 DUF1493 family protein -
PTC84_RS20190 (PTC84_20190) 4170483..4170731 - 249 Protein_3947 type VI secretion system tube protein Hcp -
PTC84_RS20195 (PTC84_20195) 4170804..4171892 - 1089 WP_023295682.1 AAA family ATPase -
PTC84_RS20200 (PTC84_20200) 4172039..4172998 - 960 WP_047734930.1 DUF523 and DUF1722 domain-containing protein -
PTC84_RS20205 (PTC84_20205) 4173101..4173511 - 411 WP_017383647.1 hydroxyisourate hydrolase -
PTC84_RS20210 (PTC84_20210) 4173611..4174336 - 726 WP_015570074.1 MerR family transcriptional regulator -
PTC84_RS20215 (PTC84_20215) 4174454..4174978 + 525 WP_032652079.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10089.65 Da        Isoelectric Point: 7.8740

>T272250 WP_032103793.1 NZ_CP117750:4169811-4170065 [Enterobacter hormaechei]
VKITWSEEAWEDYLYWQETDKRMVKKINELIKISCRTPFEGIGKPEPLKHNLAGFWSRRITSEHRMVYAITEEAILIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9313.55 Da        Isoelectric Point: 4.7854

>AT272250 WP_032103791.1 NZ_CP117750:4169563-4169814 [Enterobacter hormaechei]
MRVISYSEARQNLSATMVQTTEDRAPVLITRQNGESCVLMSLEEYNSLEETAYLMRSPANAKRLMNSIESLKSGGGKERD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References