Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3803589..3803847 Replicon chromosome
Accession NZ_CP117678
Organism Escherichia albertii strain BIA_4

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS033_RS18715 Protein ID WP_000809168.1
Coordinates 3803589..3803741 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3803790..3803847 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS033_RS18700 3799000..3800916 + 1917 WP_000516135.1 molecular chaperone DnaK -
PS033_RS18705 3801005..3802135 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS033_RS18710 3802398..3803511 - 1114 Protein_3649 IS4-like element IS421 family transposase -
PS033_RS18715 3803589..3803741 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3803790..3803847 + 58 - - Antitoxin
PS033_RS18720 3804363..3805124 + 762 WP_059267799.1 outer membrane protein OmpK -
PS033_RS18725 3805145..3806638 + 1494 Protein_3652 sulfatase-like hydrolase/transferase -
PS033_RS18730 3806792..3808039 + 1248 WP_059267798.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T272012 WP_000809168.1 NZ_CP117678:c3803741-3803589 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT272012 NZ_CP117678:3803790-3803847 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References