Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-timR/SymE(toxin)
Location 3732918..3733330 Replicon chromosome
Accession NZ_CP117668
Organism Escherichia albertii strain BIA_11

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS054_RS18410 Protein ID WP_124866422.1
Coordinates 3732918..3733259 (-) Length 114 a.a.

Antitoxin (RNA)


Gene name timR
Locus tag -
Coordinates 3733254..3733330 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS054_RS18390 (3728391) 3728391..3728879 + 489 Protein_3583 Rpn family recombination-promoting nuclease/putative transposase -
PS054_RS18395 (3729197) 3729197..3730275 + 1079 Protein_3584 DUF1998 domain-containing protein -
PS054_RS18400 (3730331) 3730331..3731377 - 1047 WP_072249344.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS054_RS18405 (3731377) 3731377..3732756 - 1380 WP_124866423.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS054_RS18410 (3732918) 3732918..3733259 - 342 WP_124866422.1 endoribonuclease SymE Toxin
- (3733254) 3733254..3733330 + 77 NuclAT_10 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_10 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_10 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_10 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_9 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_9 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_9 - Antitoxin
- (3733254) 3733254..3733330 + 77 NuclAT_9 - Antitoxin
PS054_RS18415 (3733487) 3733487..3734836 - 1350 WP_113649426.1 restriction endonuclease subunit S -
PS054_RS18420 (3734833) 3734833..3736422 - 1590 WP_113649427.1 type I restriction-modification system methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12338.18 Da        Isoelectric Point: 8.4951

>T271966 WP_124866422.1 NZ_CP117668:c3733259-3732918 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFVTGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVRDFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271966 NZ_CP117668:3733254-3733330 [Escherichia albertii]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References