Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) ralRA/-
Location 566952..567322 Replicon chromosome
Accession NZ_CP117668
Organism Escherichia albertii strain BIA_11

Toxin (Protein)


Gene name ralR Uniprot ID -
Locus tag PS054_RS03030 Protein ID WP_273814798.1
Coordinates 567128..567322 (-) Length 65 a.a.

Antitoxin (RNA)


Gene name ralA
Locus tag -
Coordinates 566952..567129 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS054_RS03000 (562728) 562728..562901 + 174 WP_032275239.1 protein YnaL -
PS054_RS03005 (562931) 562931..564304 + 1374 WP_059268187.1 ATP-dependent RNA helicase DbpA -
PS054_RS03010 (564408) 564408..565343 - 936 WP_044712357.1 tRNA 2-thiocytidine(32) synthetase TtcA -
PS054_RS03015 (565395) 565395..566630 - 1236 WP_059221776.1 site-specific integrase -
PS054_RS03020 (566632) 566632..566847 - 216 WP_048969784.1 excisionase XisR -
- (566952) 566952..567129 + 178 NuclAT_0 - Antitoxin
- (566952) 566952..567129 + 178 NuclAT_0 - Antitoxin
- (566952) 566952..567129 + 178 NuclAT_0 - Antitoxin
- (566952) 566952..567129 + 178 NuclAT_0 - Antitoxin
PS054_RS03025 (566947) 566947..567135 - 189 WP_273814796.1 DUF1187 family protein -
PS054_RS03030 (567128) 567128..567322 - 195 WP_273814798.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR Toxin
PS054_RS03035 (567387) 567387..568439 - 1053 WP_273814800.1 RecT family recombinase -
PS054_RS03040 (568451) 568451..571612 - 3162 WP_273814803.1 exodeoxyribonuclease VIII -
PS054_RS03045 (571713) 571713..571987 - 275 Protein_602 hypothetical protein -
PS054_RS03050 (572062) 572062..572232 - 171 WP_273814805.1 YdaE family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 565395..609143 43748


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-54)


Sequences


Toxin        


Download         Length: 65 a.a.        Molecular weight: 7114.11 Da        Isoelectric Point: 8.9276

>T271949 WP_273814798.1 NZ_CP117668:c567322-567128 [Escherichia albertii]
MRYEKVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSDKEALERWNKRTAENINGGIYV

Download         Length: 195 bp


Antitoxin


Download         Length: 178 bp

>AT271949 NZ_CP117668:566952-567129 [Escherichia albertii]
AGGAATGAAGTTTCTCGCAATTAAAATTCATCAGTTTTACTTTTTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCTGAG
AGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTACCACCTTCCTTTTC
AATTGTGGCGGTAATTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References