Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1050071..1050315 Replicon chromosome
Accession NZ_CP117654
Organism Escherichia albertii strain BIA_15

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS036_RS05020 Protein ID WP_000956458.1
Coordinates 1050163..1050315 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1050071..1050118 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS036_RS05005 1045474..1047273 + 1800 WP_059275529.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS036_RS05010 1047273..1048985 + 1713 WP_059275528.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS036_RS05015 1049165..1049899 + 735 WP_001125132.1 phosphoadenosine phosphosulfate reductase -
- 1050071..1050118 - 48 - - Antitoxin
PS036_RS05020 1050163..1050315 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS036_RS05025 1050508..1051620 - 1113 WP_095574181.1 IS4-like element IS421 family transposase -
PS036_RS05030 1051873..1054530 + 2658 WP_059221338.1 CRISPR-associated helicase/endonuclease Cas3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271891 WP_000956458.1 NZ_CP117654:1050163-1050315 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 48 bp

>AT271891 NZ_CP117654:c1050118-1050071 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References