Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-OrzO/SymE(toxin)
Location 4052213..4052625 Replicon chromosome
Accession NZ_CP117647
Organism Escherichia albertii strain BIA_16-3

Toxin (Protein)


Gene name symE Uniprot ID A0A828GM97
Locus tag PS048_RS19850 Protein ID WP_054409947.1
Coordinates 4052284..4052625 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name OrzO
Locus tag -
Coordinates 4052213..4052289 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS048_RS19840 (4047353) 4047353..4048711 + 1359 WP_273785054.1 restriction endonuclease subunit S -
PS048_RS19845 (4048806) 4048806..4052069 + 3264 WP_273785056.1 HsdR family type I site-specific deoxyribonuclease -
- (4052213) 4052213..4052289 - 77 NuclAT_4 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_4 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_4 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_4 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_5 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_5 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_5 - Antitoxin
- (4052213) 4052213..4052289 - 77 NuclAT_5 - Antitoxin
PS048_RS19850 (4052284) 4052284..4052625 + 342 WP_054409947.1 endoribonuclease SymE Toxin
PS048_RS19855 (4052672) 4052672..4053529 - 858 Protein_3877 DUF1524 domain-containing protein -
PS048_RS19860 (4053715) 4053715..4054647 - 933 WP_059257983.1 Rpn family recombination-promoting nuclease/putative transposase -
PS048_RS19865 (4054834) 4054834..4056114 + 1281 WP_273785059.1 DUF445 domain-containing protein -
PS048_RS19870 (4056234) 4056234..4057385 + 1152 WP_266118556.1 double-cubane-cluster-containing anaerobic reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12309.18 Da        Isoelectric Point: 9.0984

>T271860 WP_054409947.1 NZ_CP117647:4052284-4052625 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAIDVKVMEGCIVLTAQPPAAKESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271860 NZ_CP117647:c4052289-4052213 [Escherichia albertii]
AGTCATAACTGCTATTCCTTCGAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A828GM97

Antitoxin

Download structure file

References