Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3975835..3976093 Replicon chromosome
Accession NZ_CP117647
Organism Escherichia albertii strain BIA_16-3

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS048_RS19475 Protein ID WP_000809168.1
Coordinates 3975941..3976093 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3975835..3975892 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS048_RS19460 3971643..3972890 - 1248 WP_273785025.1 cytoplasmic protein -
PS048_RS19465 3973044..3974537 - 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
PS048_RS19470 3974558..3975319 - 762 WP_059275866.1 outer membrane protein OmpK -
- 3975835..3975892 - 58 - - Antitoxin
PS048_RS19475 3975941..3976093 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS048_RS19480 3976201..3977331 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS048_RS19485 3977420..3979336 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS048_RS19490 3979711..3980115 + 405 WP_000833521.1 DUF2541 family protein -
PS048_RS19495 3980142..3980855 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271858 WP_000809168.1 NZ_CP117647:3975941-3976093 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271858 NZ_CP117647:c3975892-3975835 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References