Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1097081..1097327 Replicon chromosome
Accession NZ_CP117647
Organism Escherichia albertii strain BIA_16-3

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS048_RS05235 Protein ID WP_000956458.1
Coordinates 1097175..1097327 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1097081..1097133 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS048_RS05220 1092485..1094284 + 1800 WP_273785847.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS048_RS05225 1094284..1095996 + 1713 WP_059273794.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS048_RS05230 1096176..1096910 + 735 WP_025238482.1 phosphoadenosine phosphosulfate reductase -
- 1097081..1097133 - 53 - - Antitoxin
PS048_RS05235 1097175..1097327 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS048_RS05240 1097453..1098490 - 1038 WP_059258200.1 alkaline phosphatase isozyme conversion aminopeptidase -
PS048_RS05245 1098743..1099651 + 909 WP_000372395.1 sulfate adenylyltransferase subunit CysD -
PS048_RS05250 1099653..1101080 + 1428 WP_001090334.1 sulfate adenylyltransferase subunit CysN -
PS048_RS05255 1101080..1101685 + 606 WP_059221476.1 adenylyl-sulfate kinase -
PS048_RS05260 1101735..1102058 + 324 WP_131109461.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271848 WP_000956458.1 NZ_CP117647:1097175-1097327 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT271848 NZ_CP117647:c1097133-1097081 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References