Detailed information of TA system TA271842

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 181936..182193
• Replicon: chromosome
• Accession: NZ_CP117647
• Organism: Escherichia albertii strain BIA_16-3

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: -
• Locus tag: PS048_RS00860
• Protein ID: WP_273785483.1
• Coordinates: 182041..182193 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokX
Locus tag	-
Coordinates	181936..181990 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS048_RS00840	177166..178161	-	996	WP_059229190.1	acyltransferase	-
PS048_RS00845	178334..178633	+	300	WP_000979961.1	YsaB family lipoprotein	-
PS048_RS00850	178729..179640	+	912	WP_001168544.1	glycine--tRNA ligase subunit alpha	-
PS048_RS00855	179650..181719	+	2070	WP_059221279.1	glycine--tRNA ligase subunit beta	-
-	181936..181990	-	55	-	-	Antitoxin
PS048_RS00860	182041..182193	+	153	WP_273785483.1	type I toxin-antitoxin system toxin HokA	Toxin
PS048_RS00865	182345..183031	+	687	WP_273785484.1	hypothetical protein	-
PS048_RS00870	183099..183311	-	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
PS048_RS00875	183594..183884	-	291	WP_000455794.1	HTH-type transcriptional regulator	-
PS048_RS00880	184307..185017	+	711	WP_002460072.1	DUF3053 domain-containing protein	-
PS048_RS00885	185070..186044	-	975	WP_207610283.1	glyoxylate/hydroxypyruvate reductase GhrB	-
PS048_RS00890	186148..186807	-	660	WP_000747625.1	OmpA family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (5-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5836.05 Da
• Isoelectric Point: 8.7820

>T271842 WP_273785483.1 NZ_CP117647:182041-182193 [Escherichia albertii]
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSNELATFLACGNKK

Nucleotide

• Length: 153 bp

Antitoxin

Nucleotide

• Length: 55 bp

>AT271842 NZ_CP117647:c181990-181936 [Escherichia albertii]
GTTCAGGCATAGGGTAGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin