Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-timR/SymE(toxin)
Location 4129920..4130332 Replicon chromosome
Accession NZ_CP117643
Organism Escherichia albertii strain BIA_17

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag PS043_RS20815 Protein ID WP_000132619.1
Coordinates 4129991..4130332 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name timR
Locus tag -
Coordinates 4129920..4129996 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS043_RS20805 (4126821) 4126821..4128410 + 1590 WP_157704341.1 type I restriction-modification system methyltransferase -
PS043_RS20810 (4128407) 4128407..4129762 + 1356 WP_161537581.1 restriction endonuclease subunit S -
- (4129920) 4129920..4129996 - 77 NuclAT_10 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_10 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_10 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_10 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_9 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_9 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_9 - Antitoxin
- (4129920) 4129920..4129996 - 77 NuclAT_9 - Antitoxin
PS043_RS20815 (4129991) 4129991..4130332 + 342 WP_000132619.1 endoribonuclease SymE Toxin
PS043_RS20820 (4130494) 4130494..4131873 + 1380 WP_059217670.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS043_RS20825 (4131873) 4131873..4132919 + 1047 WP_072252312.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS043_RS20830 (4132975) 4132975..4134053 - 1079 Protein_4080 DUF1998 domain-containing protein -
PS043_RS20835 (4134370) 4134370..4135301 - 932 Protein_4081 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T271829 WP_000132619.1 NZ_CP117643:4129991-4130332 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271829 NZ_CP117643:c4129996-4129920 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References