Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4053094..4053352 Replicon chromosome
Accession NZ_CP117643
Organism Escherichia albertii strain BIA_17

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS043_RS20445 Protein ID WP_000809168.1
Coordinates 4053200..4053352 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4053094..4053151 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS043_RS20430 4048901..4050148 - 1248 WP_059227922.1 hypothetical protein -
PS043_RS20435 4050302..4051795 - 1494 WP_059216552.1 sulfatase-like hydrolase/transferase -
PS043_RS20440 4051816..4052577 - 762 WP_273816559.1 outer membrane protein OmpK -
- 4053094..4053151 - 58 - - Antitoxin
PS043_RS20445 4053200..4053352 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS043_RS20450 4053456..4054586 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS043_RS20455 4054675..4056591 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS043_RS20460 4056966..4057370 + 405 WP_000833521.1 DUF2541 family protein -
PS043_RS20465 4057397..4058110 + 714 WP_273816560.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271828 WP_000809168.1 NZ_CP117643:4053200-4053352 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271828 NZ_CP117643:c4053151-4053094 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References