Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1071686..1071932 Replicon chromosome
Accession NZ_CP117643
Organism Escherichia albertii strain BIA_17

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS043_RS05225 Protein ID WP_000956458.1
Coordinates 1071780..1071932 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1071686..1071738 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS043_RS05210 1067090..1068889 + 1800 WP_161538125.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS043_RS05215 1068889..1070601 + 1713 WP_273816797.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS043_RS05220 1070781..1071515 + 735 WP_161538127.1 phosphoadenosine phosphosulfate reductase -
- 1071686..1071738 - 53 - - Antitoxin
PS043_RS05225 1071780..1071932 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS043_RS05230 1072058..1073095 - 1038 WP_059268554.1 alkaline phosphatase isozyme conversion aminopeptidase -
PS043_RS05235 1073349..1074257 + 909 WP_273816798.1 sulfate adenylyltransferase subunit CysD -
PS043_RS05240 1074259..1075686 + 1428 WP_262939535.1 sulfate adenylyltransferase subunit CysN -
PS043_RS05245 1075686..1076291 + 606 WP_024164730.1 adenylyl-sulfate kinase -
PS043_RS05250 1076341..1076664 + 324 WP_001246114.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271818 WP_000956458.1 NZ_CP117643:1071780-1071932 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT271818 NZ_CP117643:c1071738-1071686 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References