Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) symE-agrB/SymE(toxin)
Location 4155823..4156236 Replicon chromosome
Accession NZ_CP117637
Organism Escherichia albertii strain BIA_18

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag PS040_RS20575 Protein ID WP_000132619.1
Coordinates 4155895..4156236 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name agrB
Locus tag -
Coordinates 4155823..4155900 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS040_RS20565 (4152725) 4152725..4154314 + 1590 WP_059216569.1 type I restriction-modification system methyltransferase -
PS040_RS20570 (4154311) 4154311..4155666 + 1356 WP_059216570.1 restriction endonuclease subunit S -
- (4155823) 4155823..4155900 - 78 NuclAT_5 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_5 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_5 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_5 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_6 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_6 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_6 - Antitoxin
- (4155823) 4155823..4155900 - 78 NuclAT_6 - Antitoxin
PS040_RS20575 (4155895) 4155895..4156236 + 342 WP_000132619.1 endoribonuclease SymE Toxin
PS040_RS20580 (4156398) 4156398..4157777 + 1380 WP_273782439.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS040_RS20585 (4157777) 4157777..4158823 + 1047 WP_015953744.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS040_RS20590 (4158879) 4158879..4159957 - 1079 Protein_4026 DUF1998 domain-containing protein -
PS040_RS20595 (4160272) 4160272..4161204 - 933 WP_273782440.1 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(20-71)


Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T271803 WP_000132619.1 NZ_CP117637:4155895-4156236 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp


Antitoxin


Download         Length: 78 bp

>AT271803 NZ_CP117637:c4155900-4155823 [Escherichia albertii]
AGTCATAACTGCTATTCCTTGGAAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References