Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4077772..4078030 Replicon chromosome
Accession NZ_CP117637
Organism Escherichia albertii strain BIA_18

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS040_RS20200 Protein ID WP_000809168.1
Coordinates 4077878..4078030 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4077772..4077829 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS040_RS20185 4073580..4074827 - 1248 WP_273782426.1 cytoplasmic protein -
PS040_RS20190 4074981..4076474 - 1494 WP_273782427.1 sulfatase-like hydrolase/transferase -
PS040_RS20195 4076495..4077256 - 762 WP_105198098.1 outer membrane protein OmpK -
- 4077772..4077829 - 58 - - Antitoxin
PS040_RS20200 4077878..4078030 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS040_RS20205 4078134..4079264 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS040_RS20210 4079353..4081269 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS040_RS20215 4081644..4082048 + 405 WP_273782428.1 DUF2541 family protein -
PS040_RS20220 4082075..4082788 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271802 WP_000809168.1 NZ_CP117637:4077878-4078030 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271802 NZ_CP117637:c4077829-4077772 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References