Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1060477..1060722 Replicon chromosome
Accession NZ_CP117637
Organism Escherichia albertii strain BIA_18

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS040_RS05060 Protein ID WP_000956458.1
Coordinates 1060570..1060722 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1060477..1060525 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS040_RS05045 1055881..1057680 + 1800 WP_273783088.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS040_RS05050 1057680..1059392 + 1713 WP_001290735.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS040_RS05055 1059572..1060306 + 735 WP_001125131.1 phosphoadenosine phosphosulfate reductase -
- 1060477..1060525 - 49 - - Antitoxin
PS040_RS05060 1060570..1060722 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS040_RS05065 1060915..1062027 - 1113 WP_273783089.1 IS4 family transposase -
PS040_RS05070 1062280..1064937 + 2658 WP_273783090.1 CRISPR-associated helicase Cas3' -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271794 WP_000956458.1 NZ_CP117637:1060570-1060722 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 49 bp

>AT271794 NZ_CP117637:c1060525-1060477 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References