Detailed information of TA system TA271733

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 2064425..2064795
• Replicon: chromosome
• Accession: NZ_CP117620
• Organism: Escherichia albertii strain BIA_24

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: -
• Locus tag: PS039_RS09905
• Protein ID: WP_059278633.1
• Coordinates: 2064601..2064795 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	2064425..2064602 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS039_RS09875 (2060203)	2060203..2060376	+	174	WP_032275239.1	protein YnaL	-
PS039_RS09880 (2060406)	2060406..2061779	+	1374	WP_000123704.1	ATP-dependent RNA helicase DbpA	-
PS039_RS09885 (2061882)	2061882..2062817	-	936	WP_044712357.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
PS039_RS09890 (2062869)	2062869..2064104	-	1236	WP_072249326.1	site-specific integrase	-
PS039_RS09895 (2064106)	2064106..2064321	-	216	WP_048969784.1	excisionase XisR	-
- (2064425)	2064425..2064602	+	178	NuclAT_0	-	Antitoxin
- (2064425)	2064425..2064602	+	178	NuclAT_0	-	Antitoxin
- (2064425)	2064425..2064602	+	178	NuclAT_0	-	Antitoxin
- (2064425)	2064425..2064602	+	178	NuclAT_0	-	Antitoxin
PS039_RS09900 (2064420)	2064420..2064608	-	189	WP_059278634.1	DUF1187 family protein	-
PS039_RS09905 (2064601)	2064601..2064795	-	195	WP_059278633.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
PS039_RS09910 (2064860)	2064860..2065954	-	1095	WP_273810513.1	RecT family recombinase	-
PS039_RS09915 (2065969)	2065969..2069094	-	3126	WP_059278632.1	exodeoxyribonuclease VIII	-
PS039_RS09920 (2069194)	2069194..2069469	-	276	WP_059278631.1	hypothetical protein	-
PS039_RS09925 (2069544)	2069544..2069714	-	171	WP_076741965.1	YdaE family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2062869..2106274	43405

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7068.10 Da
• Isoelectric Point: 8.7468

>T271733 WP_059278633.1 NZ_CP117620:c2064795-2064601 [Escherichia albertii]
MRYEKVKPCPFCGCPSVTVKAISGCYRAKCNGCESRTGYGGSEKEALERWNKRTAENINGGIYV

Nucleotide

• Length: 195 bp

Antitoxin

Nucleotide

• Length: 178 bp

>AT271733 NZ_CP117620:2064425-2064602 [Escherichia albertii]
AGGACTGAAGTTTCTCGCAATTAAAATTCATCAGTTTTACATTTTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCTGAG
AGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTACCTCCTTCCTTTTC
AATTGTGGCGGTAATTTT

Structures

Antitoxin