Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3993235..3993493 Replicon chromosome
Accession NZ_CP117615
Organism Escherichia albertii strain BIA_25

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS046_RS19415 Protein ID WP_000809168.1
Coordinates 3993341..3993493 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3993235..3993292 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS046_RS19400 3989043..3990290 - 1248 WP_095573584.1 cytoplasmic protein -
PS046_RS19405 3990444..3991937 - 1494 WP_095573583.1 sulfatase-like hydrolase/transferase -
PS046_RS19410 3991958..3992719 - 762 WP_095573582.1 outer membrane protein OmpK -
- 3993235..3993292 - 58 - - Antitoxin
PS046_RS19415 3993341..3993493 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS046_RS19420 3993571..3994683 + 1113 WP_095573581.1 IS4-like element IS421 family transposase -
PS046_RS19425 3994946..3996076 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS046_RS19430 3996165..3998081 - 1917 WP_000516135.1 molecular chaperone DnaK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271718 WP_000809168.1 NZ_CP117615:3993341-3993493 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271718 NZ_CP117615:c3993292-3993235 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References