Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3801931..3802189 Replicon chromosome
Accession NZ_CP117609
Organism Escherichia albertii strain BIA_26

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS038_RS18205 Protein ID WP_000809168.1
Coordinates 3802037..3802189 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokW
Locus tag -
Coordinates 3801931..3801988 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS038_RS18190 3797749..3798996 - 1248 WP_025237694.1 hypothetical protein -
PS038_RS18195 3799150..3800643 - 1494 WP_059218488.1 sulfatase-like hydrolase/transferase -
PS038_RS18200 3800664..3801425 - 762 WP_001276206.1 outer membrane protein OmpK -
- 3801931..3801988 - 58 - - Antitoxin
PS038_RS18205 3802037..3802189 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS038_RS18210 3802297..3803427 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS038_RS18215 3803516..3805432 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS038_RS18220 3805807..3806211 + 405 WP_000833521.1 DUF2541 family protein -
PS038_RS18225 3806238..3806951 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271687 WP_000809168.1 NZ_CP117609:3802037-3802189 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271687 NZ_CP117609:c3801988-3801931 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References