Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1056224..1056470 Replicon chromosome
Accession NZ_CP117609
Organism Escherichia albertii strain BIA_26

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS038_RS05020 Protein ID WP_000956458.1
Coordinates 1056318..1056470 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1056224..1056276 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS038_RS05005 1051628..1053427 + 1800 WP_059218033.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS038_RS05010 1053427..1055139 + 1713 WP_059218032.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS038_RS05015 1055319..1056053 + 735 WP_059218031.1 phosphoadenosine phosphosulfate reductase -
- 1056224..1056276 - 53 - - Antitoxin
PS038_RS05020 1056318..1056470 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS038_RS05025 1056596..1057633 - 1038 WP_059218030.1 alkaline phosphatase isozyme conversion aminopeptidase -
PS038_RS05030 1057887..1058795 + 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
PS038_RS05035 1058797..1060224 + 1428 WP_059218029.1 sulfate adenylyltransferase subunit CysN -
PS038_RS05040 1060224..1060829 + 606 WP_024164730.1 adenylyl-sulfate kinase -
PS038_RS05045 1060879..1061202 + 324 WP_044711292.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271676 WP_000956458.1 NZ_CP117609:1056318-1056470 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT271676 NZ_CP117609:c1056276-1056224 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References