Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4462318..4462576 Replicon chromosome
Accession NZ_CP117606
Organism Escherichia albertii strain BIA_29

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag PS031_RS21655 Protein ID WP_001519334.1
Coordinates 4462318..4462470 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4462519..4462576 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS031_RS21635 4457560..4458273 - 714 WP_204628791.1 acidic protein MsyB -
PS031_RS21640 4458300..4458704 - 405 WP_273771206.1 DUF2541 family protein -
PS031_RS21645 4459079..4460995 + 1917 WP_000516137.1 molecular chaperone DnaK -
PS031_RS21650 4461084..4462214 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS031_RS21655 4462318..4462470 - 153 WP_001519334.1 type I toxin-antitoxin system toxin MokC Toxin
- 4462519..4462576 + 58 - - Antitoxin
PS031_RS21660 4463092..4463853 + 762 WP_208625529.1 outer membrane protein OmpK -
PS031_RS21665 4463874..4465367 + 1494 WP_204628790.1 sulfatase-like hydrolase/transferase -
PS031_RS21670 4465521..4466768 + 1248 WP_262931223.1 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5515.59 Da        Isoelectric Point: 7.1312

>T271665 WP_001519334.1 NZ_CP117606:c4462470-4462318 [Escherichia albertii]
MKQHKAMIIALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271665 NZ_CP117606:4462519-4462576 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References