Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symER/SymE(toxin)
Location 4387418..4387831 Replicon chromosome
Accession NZ_CP117606
Organism Escherichia albertii strain BIA_29

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS031_RS21290 Protein ID WP_059250864.1
Coordinates 4387418..4387759 (-) Length 114 a.a.

Antitoxin (RNA)


Gene name symR
Locus tag -
Coordinates 4387754..4387831 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS031_RS21270 (4383793) 4383793..4384725 + 933 WP_204628804.1 Rpn family recombination-promoting nuclease/putative transposase -
PS031_RS21275 (4384877) 4384877..4385050 - 174 Protein_4144 GntR family transcriptional regulator -
PS031_RS21280 (4385275) 4385275..4386151 + 877 Protein_4145 DUF262 domain-containing protein -
PS031_RS21285 (4386205) 4386205..4387371 + 1167 WP_273771112.1 DUF1524 domain-containing protein -
PS031_RS21290 (4387418) 4387418..4387759 - 342 WP_059250864.1 endoribonuclease SymE Toxin
- (4387754) 4387754..4387831 + 78 NuclAT_8 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_8 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_8 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_8 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_9 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_9 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_9 - Antitoxin
- (4387754) 4387754..4387831 + 78 NuclAT_9 - Antitoxin
PS031_RS21295 (4387988) 4387988..4389373 - 1386 WP_059257978.1 restriction endonuclease subunit S -
PS031_RS21300 (4389370) 4389370..4390959 - 1590 WP_074463834.1 type I restriction-modification system methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12326.12 Da        Isoelectric Point: 7.8219

>T271663 WP_059250864.1 NZ_CP117606:c4387759-4387418 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTTQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 78 bp

>AT271663 NZ_CP117606:4387754-4387831 [Escherichia albertii]
AGTCATAACTGCTATTCCTTGGAAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References