Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2618777..2619023 Replicon chromosome
Accession NZ_CP117606
Organism Escherichia albertii strain BIA_29

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS031_RS12890 Protein ID WP_000956458.1
Coordinates 2618777..2618929 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 2618971..2619023 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS031_RS12880 2614671..2615708 + 1038 WP_059253936.1 aminopeptidase -
PS031_RS12885 2616043..2618582 - 2540 Protein_2519 CRISPR-associated helicase Cas3' -
PS031_RS12890 2618777..2618929 - 153 WP_000956458.1 Hok/Gef family protein Toxin
- 2618971..2619023 + 53 - - Antitoxin
PS031_RS12895 2619194..2619928 - 735 WP_001125132.1 phosphoadenosine phosphosulfate reductase -
PS031_RS12900 2620108..2621820 - 1713 WP_131109610.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS031_RS12905 2621820..2623619 - 1800 WP_131109609.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271654 WP_000956458.1 NZ_CP117606:c2618929-2618777 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT271654 NZ_CP117606:2618971-2619023 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References