Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3834364..3834622 Replicon chromosome
Accession NZ_CP117600
Organism Escherichia albertii strain BIA_32

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS047_RS18990 Protein ID WP_000809168.1
Coordinates 3834364..3834516 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3834565..3834622 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS047_RS18975 3829775..3831691 + 1917 WP_059222122.1 molecular chaperone DnaK -
PS047_RS18980 3831780..3832910 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS047_RS18985 3833173..3834286 - 1114 Protein_3699 IS4-like element IS421 family transposase -
PS047_RS18990 3834364..3834516 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3834565..3834622 + 58 - - Antitoxin
PS047_RS18995 3835138..3835899 + 762 WP_059278348.1 outer membrane protein OmpK -
PS047_RS19000 3835920..3837413 + 1494 WP_059278347.1 sulfatase-like hydrolase/transferase -
PS047_RS19005 3837567..3838814 + 1248 WP_059267798.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - espX1 3833173..3842752 9579


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271637 WP_000809168.1 NZ_CP117600:c3834516-3834364 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271637 NZ_CP117600:3834565-3834622 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References