Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2021951..2022177 Replicon chromosome
Accession NZ_CP117600
Organism Escherichia albertii strain BIA_32

Toxin (Protein)


Gene name hokX Uniprot ID -
Locus tag PS047_RS10415 Protein ID WP_273823841.1
Coordinates 2021951..2022085 (-) Length 45 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 2022130..2022177 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS047_RS10405 2017736..2020393 - 2658 WP_059221338.1 CRISPR-associated helicase/endonuclease Cas3 -
PS047_RS10410 2020646..2021758 + 1113 WP_273823840.1 IS4-like element IS421 family transposase -
PS047_RS10415 2021951..2022085 - 135 WP_273823841.1 Hok/Gef family protein Toxin
- 2022130..2022177 + 48 - - Antitoxin
PS047_RS10420 2022349..2023083 - 735 WP_001125132.1 phosphoadenosine phosphosulfate reductase -
PS047_RS10425 2023162..2024874 - 1713 WP_059221001.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS047_RS10430 2024874..2026673 - 1800 WP_059221004.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-40)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4927.99 Da        Isoelectric Point: 7.6784

>T271632 WP_273823841.1 NZ_CP117600:c2022085-2021951 [Escherichia albertii]
MLTKIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 135 bp

Antitoxin


Download         Length: 48 bp

>AT271632 NZ_CP117600:2022130-2022177 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References