Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-ohsC/SymE(toxin)
Location 4000803..4001215 Replicon chromosome
Accession NZ_CP117595
Organism Escherichia albertii strain BIA_35

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS050_RS19325 Protein ID WP_000132603.1
Coordinates 4000874..4001215 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 4000803..4000879 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS050_RS19315 (3997726) 3997726..3999312 + 1587 WP_001063209.1 type I restriction-modification system methyltransferase -
PS050_RS19320 (3999312) 3999312..4000646 + 1335 WP_000052067.1 restriction endonuclease subunit S -
- (4000803) 4000803..4000879 - 77 NuclAT_8 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_8 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_8 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_8 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_9 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_9 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_9 - Antitoxin
- (4000803) 4000803..4000879 - 77 NuclAT_9 - Antitoxin
PS050_RS19325 (4000874) 4000874..4001215 + 342 WP_000132603.1 endoribonuclease SymE Toxin
PS050_RS19330 (4001377) 4001377..4002756 + 1380 WP_010341339.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS050_RS19335 (4002756) 4002756..4003802 + 1047 WP_015953744.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS050_RS19340 (4003858) 4003858..4004936 - 1079 Protein_3787 DUF1998 domain-containing protein -
PS050_RS19345 (4005251) 4005251..4006183 - 933 WP_059255468.1 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12246.04 Da        Isoelectric Point: 7.8259

>T271606 WP_000132603.1 NZ_CP117595:4000874-4001215 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRSPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271606 NZ_CP117595:c4000879-4000803 [Escherichia albertii]
AGTCATGATTACTATTCTCGTGAAATAGGGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References