Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3703905..3704555 Replicon chromosome
Accession NZ_CP117590
Organism Escherichia albertii strain BIA_36

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PS051_RS18515 Protein ID WP_149508045.1
Coordinates 3704214..3704555 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PS051_RS18510 Protein ID WP_273781312.1
Coordinates 3703905..3704204 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS051_RS18485 (3699120) 3699120..3699431 - 312 WP_000410252.1 hypothetical protein -
PS051_RS18490 (3699436) 3699436..3699828 - 393 WP_000273381.1 flagellar export chaperone FliS -
PS051_RS18495 (3699851) 3699851..3701167 - 1317 WP_273781308.1 flagellar filament capping protein FliD -
PS051_RS18500 (3701594) 3701594..3702508 - 915 WP_273781310.1 lateral flagellin LafA -
PS051_RS18505 (3702995) 3702995..3703847 + 853 Protein_3616 winged helix-turn-helix domain-containing protein -
PS051_RS18510 (3703905) 3703905..3704204 - 300 WP_273781312.1 helix-turn-helix transcriptional regulator Antitoxin
PS051_RS18515 (3704214) 3704214..3704555 - 342 WP_149508045.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS051_RS18520 (3704631) 3704631..3705608 - 978 WP_273781313.1 flagellar hook-associated protein -
PS051_RS18525 (3705625) 3705625..3706554 - 930 WP_025237548.1 flagellar hook-associated protein FlgL -
PS051_RS18530 (3706569) 3706569..3707945 - 1377 WP_273781314.1 flagellar hook-associated protein FlgK -
PS051_RS18535 (3708134) 3708134..3708433 - 300 WP_000867179.1 rod-binding protein -
PS051_RS18540 (3708433) 3708433..3709533 - 1101 WP_273781315.1 flagellar basal body P-ring protein FlgI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-107)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12972.79 Da        Isoelectric Point: 5.7334

>T271579 WP_149508045.1 NZ_CP117590:c3704555-3704214 [Escherichia albertii]
MWDVETTETFDNWFDAQTVALKEDLLAAMLILAEYGPQLGRPFADTVNDSQFSNMKELRVQHQGNPVRAFFAFDPARRGI
VLCAGDKTGLNEKKFYRDMIKLADSEYPKHLKK

Download         Length: 342 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10926.71 Da        Isoelectric Point: 9.7665

>AT271579 WP_273781312.1 NZ_CP117590:c3704204-3703905 [Escherichia albertii]
MATLKELIAKQSPESQARIAAKVEEMRQTIALHQLREELNISQTEMAAAMGIKQPTLAKIEQADNDPRLSTLKRYVAALG
GELSIDVKLPNGKRVAFQI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References