Detailed information of TA system TA271572

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 2516228..2516634
• Replicon: chromosome
• Accession: NZ_CP117590
• Organism: Escherichia albertii strain BIA_36

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: -
• Locus tag: PS051_RS12640
• Protein ID: WP_059268219.1
• Coordinates: 2516228..2516458 (+)
• Length: 77 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	2516457..2516634 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS051_RS12605 (2511521)	2511521..2512081	-	561	WP_059217651.1	T3SS effector NleG family protein	-
PS051_RS12610 (2512196)	2512196..2512375	-	180	Protein_2465	phage tail fiber C-terminal domain-containing protein	-
PS051_RS12615 (2513132)	2513132..2513470	-	339	Protein_2466	prophage tail fiber N-terminal domain-containing protein	-
PS051_RS12620 (2513531)	2513531..2514655	-	1125	Protein_2467	DUF1983 domain-containing protein	-
PS051_RS12625 (2514644)	2514644..2514769	+	126	Protein_2468	host-nuclease inhibitor Gam family protein	-
PS051_RS12630 (2514775)	2514775..2515554	+	780	WP_000100866.1	phage recombination protein Bet	-
PS051_RS12635 (2515551)	2515551..2516231	+	681	WP_059279422.1	YqaJ viral recombinase family protein	-
PS051_RS12640 (2516228)	2516228..2516458	+	231	WP_059268219.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
- (2516457)	2516457..2516634	-	178	NuclAT_1	-	Antitoxin
- (2516457)	2516457..2516634	-	178	NuclAT_1	-	Antitoxin
- (2516457)	2516457..2516634	-	178	NuclAT_1	-	Antitoxin
- (2516457)	2516457..2516634	-	178	NuclAT_1	-	Antitoxin
PS051_RS12645 (2516451)	2516451..2516639	+	189	WP_048969783.1	DUF1187 family protein	-
PS051_RS12650 (2516739)	2516739..2516954	+	216	WP_048969784.1	excisionase XisR	-
PS051_RS12655 (2516956)	2516956..2518191	+	1236	WP_273780770.1	site-specific integrase	-
PS051_RS12660 (2519081)	2519081..2520034	+	954	WP_001516440.1	omptin family outer membrane protease OmpT	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2510278..2571144	60866

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (18-66)

Sequences

Toxin

Protein

• Length: 77 a.a.
• Molecular weight: 8313.48 Da
• Isoelectric Point: 9.2288

>T271572 WP_059268219.1 NZ_CP117590:2516228-2516458 [Escherichia albertii]
MSAATKLTGEKPERYTKVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTAENINGGIYV

Nucleotide

• Length: 231 bp

Antitoxin

Nucleotide

• Length: 178 bp

>AT271572 NZ_CP117590:c2516634-2516457 [Escherichia albertii]
AGGACTGAAGTTTCTCGCAATTAAAATTCATCAGTTTTACTTTTTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCTGAG
AGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTACCACCTTCCTTTTC
AATTGTGGCGGTAATTTT

Structures

Antitoxin