Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-agrB/SymE(toxin)
Location 4121301..4121713 Replicon chromosome
Accession NZ_CP117586
Organism Escherichia albertii strain BIA_40

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS042_RS20435 Protein ID WP_059225014.1
Coordinates 4121372..4121713 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name agrB
Locus tag -
Coordinates 4121301..4121377 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS042_RS20425 (4118215) 4118215..4119803 + 1589 Protein_3987 type I restriction-modification system methyltransferase -
PS042_RS20430 (4119800) 4119800..4121143 + 1344 WP_059235087.1 restriction endonuclease subunit S -
- (4121301) 4121301..4121377 - 77 NuclAT_8 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_8 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_8 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_8 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_9 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_9 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_9 - Antitoxin
- (4121301) 4121301..4121377 - 77 NuclAT_9 - Antitoxin
PS042_RS20435 (4121372) 4121372..4121713 + 342 WP_059225014.1 endoribonuclease SymE Toxin
PS042_RS20440 (4121760) 4121760..4122926 - 1167 WP_077629336.1 DUF1524 domain-containing protein -
PS042_RS20445 (4122980) 4122980..4123856 - 877 Protein_3991 DUF262 domain-containing protein -
PS042_RS20450 (4124081) 4124081..4124254 + 174 Protein_3992 GntR family transcriptional regulator -
PS042_RS20455 (4124407) 4124407..4125339 - 933 WP_059242218.1 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12384.20 Da        Isoelectric Point: 7.8219

>T271555 WP_059225014.1 NZ_CP117586:4121372-4121713 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVITGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271555 NZ_CP117586:c4121377-4121301 [Escherichia albertii]
AGTCATGATTACTATTCTCCATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References