Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4046875..4047133 Replicon chromosome
Accession NZ_CP117586
Organism Escherichia albertii strain BIA_40

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS042_RS20070 Protein ID WP_000809168.1
Coordinates 4046981..4047133 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4046875..4046932 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS042_RS20055 4042682..4043929 - 1248 WP_059235056.1 hypothetical protein -
PS042_RS20060 4044083..4045576 - 1494 WP_256875787.1 sulfatase-like hydrolase/transferase -
PS042_RS20065 4045597..4046358 - 762 WP_001276206.1 outer membrane protein OmpK -
- 4046875..4046932 - 58 - - Antitoxin
PS042_RS20070 4046981..4047133 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS042_RS20075 4047241..4048371 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS042_RS20080 4048460..4050376 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS042_RS20085 4050751..4051155 + 405 WP_000833521.1 DUF2541 family protein -
PS042_RS20090 4051182..4051895 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271553 WP_000809168.1 NZ_CP117586:4046981-4047133 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271553 NZ_CP117586:c4046932-4046875 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References