Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3755798..3756056 Replicon chromosome
Accession NZ_CP117583
Organism Escherichia albertii strain BIA_41

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS045_RS18205 Protein ID WP_000809168.1
Coordinates 3755798..3755950 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3755999..3756056 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS045_RS18185 3751036..3751749 - 714 WP_001102345.1 acidic protein MsyB -
PS045_RS18190 3751776..3752180 - 405 WP_000833521.1 DUF2541 family protein -
PS045_RS18195 3752555..3754471 + 1917 WP_000516135.1 molecular chaperone DnaK -
PS045_RS18200 3754560..3755690 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS045_RS18205 3755798..3755950 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3755999..3756056 + 58 - - Antitoxin
PS045_RS18210 3756572..3757333 + 762 WP_105198098.1 outer membrane protein OmpK -
PS045_RS18215 3757354..3758847 + 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
PS045_RS18220 3759001..3760248 + 1248 WP_059224806.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271534 WP_000809168.1 NZ_CP117583:c3755950-3755798 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271534 NZ_CP117583:3755999-3756056 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References